Mechanism of Action:
Thiocolchicoside (THIOTENSE™)
* Semi-synthetic derivative of colchicoside
* Binds to GABA-A and glycine receptors
* Acts at the supraspinal level to relieve muscle spasms
* Also exhibits anti-inflammatory and analgesic properties
* Non-sedative: preserves alertness and daily function
Aceclofenac (in THIOTENSE-AC™)
* Inhibits COX enzymes, reducing prostaglandin synthesis
* Suppresses IL-1, TNF, and PGE2—key drivers of inflammation
* Deep tissue penetration ensures targeted joint relief
Indications:
* Acute and chronic low back pain
* Cervical and lumbar spondylosis
* Muscle spasms of traumatic or rheumatic origin
* Arthritis and inflammatory joint disorders
* Fever with musculoskeletal pain
Clinical Advantages:
* Dual-action relief: muscle relaxation + inflammation control
* Non-sedative: ideal for active patients
* Fast onset and sustained comfort
* Available in 4 mg & 8 mg capsules and AC combinations
* Backed by pharmaco-EEG and animal model validation
