Centrally acting muscle relaxant for spasticity and pain relief
Mechanism of Action:
* Blocks voltage-gated sodium and calcium channels at the spinal cord level
* Inhibits presynaptic neurotransmitter release, reducing reflex muscle contractions
* Enhances skeletal muscle blood flow, relieving ischemia-induced pain
* Exhibits membrane-stabilizing and local anesthetic properties
* Provides antinociceptive activity against thermal stimulation
Indications:
* Low back pain syndrome
* Painful reflex muscle spasm
* Post-stroke spasticity
* Neurolathyrism
* Trapezitis
* Periarthritis
* Rehabilitation programs
Clinical Advantages:
* Effective in reducing muscle spasm and improving mobility
* Superior tolerability compared to thiocolchicoside in clinical trials
* Improves daily activity performance with minimal sedation
* Safe for use in elderly and comorbid patients
* 92% of patients reported no adverse events in post-marketing surveillance
* Detectable improvement in Lasegue’s score and finger-to-floor distance within 7 days
TOLPICRON™ – Calm the spasm. Restore the rhythm
Note: To be used only under the guidance of a registered medical practitioner.
