Mechanism of Action:
- Activates PPAR-α, suppressing NF-κB and pro-inflammatory cytokines
- Inhibits mast cell and microglial activation → reduces neuroinflammation
- Enhances endocannabinoid activity (CB1, CB2, TRPV1) – the “entourage effect”
- Modulates glutamate transmission and neuronal excitability
- Promotes neuroprotection and nerve regeneration
Clinical Benefits:
- Neuropathic Pain: Reduces inflammation and nerve hypersensitivity
- Diabetic Neuropathy: Decreases nerve inflammation, improves nerve conduction and reduces burning, tingling, and pain
- Fibromyalgia: Alleviates chronic widespread pain and fatigue by modulating central sensitization
- Sciatica: Reduces radicular pain and inflammation along the sciatic nerve
- Rheumatoid Arthritis: Lowers cytokine-mediated joint inflammation
- Musculoskeletal Pain: Relieves osteoarthritis and chronic muscle pain
- Migraine Prophylaxis: Helps modulate neuroinflammation and neuronal excitability, reducing migraine frequency and intensity.
- Cancer Pain: Effective adjuvant for cancer-related neuropathic pain
Key Advantages:
✅ Multi-target pain modulation
✅ Effective across neuropathic, inflammatory & nociceptive pain
✅ Excellent safety and tolerability
✅ Non-sedative & non-addictive
✅ Ideal adjunct in chronic pain management
PALMICRON™ — Multi-Pathway Relief for Neuropathic, Inflammatory & Chronic Pain
